National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Syllabus

Course Details

Subject {L-T-P / C} : LS6001 : Advanced Bioinformatics { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Prof. Bibekanand Mallick

Syllabus

Scope of bioinformatics Biological data and databases biological data (genes and proteins) annotation Sequence alignment & dynamic programming Molecular phylogeny Computational molecular biology Protein modelling Computational approaches for drug designing molecular dynamics simulations Immunoinformatics Comparative & functional genomics microarray next-generation sequencing (ChIP-seq, RNA-seq, Methyl-seq) biological networks & system biology.

Course Objectives

  • To make students acquainted with the scope and research applications of bioinformatics.

Course Outcomes

The students will be able to understand, explain and utilize the tools and databases of bioinformatics in various sub-disciplines of biological and medical sciences.

Essential Reading

  • Zhumur Ghosh, Bibekanand Mallick, Bioinformatics: Principles and Applications, Oxford University Press , ISBN-9780195692303
  • David W. Mount, Bioinformatics: Sequence and Genome Analysis, Cold Spring Harbor Laboratory Press

Supplementary Reading

  • Terence A Brown, Genomes, Oxford: Wiley-Liss
  • David P. Clark Nanette J. Pazdernik Michelle R. McGehee, Molecular Biology, Academic Cell