Course Details
Subject {L-T-P / C} : LS3405 : Genetics { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Prof. Rohan Dhiman
Syllabus
Mendelian inheritance, Mendel's experiments, symbols and terminology, dominance, recessive, monohybrid and dihybrid cross, Mendelian laws, Deviation from Mendelian inheritance - incomplete dominance, codominance, lethal, gene interaction. Linkage and crossing over, Chromosome theory of inheritance, Sex determination and inheritance, Mutation and Mutagenesis, Chromosomal variations – Numerical – Euploidy and Aneuploidy, Chromosomal Rearrangement – Deletion, Duplication, Inversion and translocation, Human genetics and genetic disorders.
Course Objectives
- To introduce the concepts of inheritance biology and understanding of the genetic terminology
- An understanding of the clinical relevance of genetic concepts
Course Outcomes
? Students will be able to explain Mendel’s principles of inheritance and apply these to problems of inheritance. <br />? Students will explain how crossing over produces recombination and use of recombination frequencies to construct a genetic map. <br />? Students will be able to list out the types of mutations and their reasons.
Essential Reading
- Snustad DP, Principles of Genetics, John Wiley, New Jersey , 5th edition (2010)
- Gardner Eldon John, Principles of Genetics, Wiley, New Delhi , 8th edition (2005)
Supplementary Reading
- Singh BD, Fundamentals of Genetics, Kalyani, Ludhiyana
- Tamarin Robert H, Principles of Genetics, Tata McGraw Hill, New Delhi , 7th edition (2012)