National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Syllabus

Course Details

Subject {L-T-P / C} : LS5410 : Molecular Genetics { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Prof. Binod Bihari Sahu

Syllabus

Mendelian inheritance, the chromosomal basis of segregation and independent assortment. Extensions and Deviations of Mendelian inheritance, pedigree analysis. Linkage and gene mapping, molecular markers, somatic cell hybrids. Extranuclear inheritance, Mutation, ploidy, Population genetics, Hardy-Weinberg principle, Speciation, Molecular evolution and genetic analysis

Course Objectives

  • Students will gain a clear, comprehensive, rigorous, balanced understanding of a set of molecular principles and experimental approach in solving a range of biological problems with an ability to think about genetic problems

Course Outcomes

Upon completing this course, <br />Students will be able to explain the main principles of Mendelian Genetics. <br />Students will be able to discuss the main methods to study gene mapping. <br />Students will be able to describe mutations and evolutionary genetics.

Essential Reading

  • Gardner EJ, Simmons, MJ, Snustad DP, Principles of Genetics, Wiley , 2011
  • Klug SK, Cummings MR, Spencer CA, Palladino MA, Concepts of Genetics, Pearson , 2012

Supplementary Reading

  • Veer Bala Rastogi, Genetics, Kedar Nath Ram Nath , 2015
  • Puehler A, Timmis, KN, Advanced Molecular Genetics, Springer Berlin Heidelberg , 2011