National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Syllabus

Course Details

Subject {L-T-P / C} : LS3303 : Biophysics { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Prof. Suman Jha

Syllabus

Physico-chemical interactions involved in biological sciences, Physico-chemical properties of water, Laws of thermodynamics and their applications, Chemico-Physical properties of biomacromolecules - Proteins, Nucleic Acids, Lipids and Carbohydrates. Thermodynamics of DNA replications, transcription, translation, Chaperon assisted protein folding and degradation of protein aggregates.

Course Objectives

  • To make the undergraduates of life science understand different but basics biological reactions, like protein folding and misfolding leading to Alzheimer's disease, happening in biological system from physico-chemical sciences point of view.

Course Outcomes

Students shall be able to understand the physico-chemical rules involved to execute the biological reactions, even the reactions happening for the first time in certain subjects.

Essential Reading

  • Pattabhi Vasantha, Biophysics, Biophysics, Narosa, New Delhi , ISBN-8173194622
  • 2. Thomas E Creighton, Proteins (Structure and Molecular Properties), W H Freeman , ISBN-978-0716770305

Supplementary Reading

  • 1. Cotterill Rodney MJ, Biophysics: a introduction, John Wiley, , ISBN-9812530088
  • Jackson MB. ., Molecular and Cellular Biophysics, Cambridge University Press , ISBN-9780511754869