National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Syllabus

Course Details

Subject {L-T-P / C} : LS4603 : Enzymology and Metabolism { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Prof. Santosh Kumar

Syllabus

Classification and nomenclature of enzymes, Mechanism of enzyme action, Regulation of enzyme activity, Kinetics, Inhibitors, Isozymes, Ribozymes, Abzymes, Bioenergetics – Oxidative and Photophosphorylation, Electron transport system and ATP synthesis. Carbohydrate Metabolism, Amino acid metabolism, Lipid metabolism, Nucleic acid metabolism, Mechanism of selective reactions, Regulation of metabolic pathways, Metabolic disorders.

Course Objectives

  • Students will gain an understanding of the basic concepts in enzymology.
  • Students will study the different metabolic pathways
  • Students will analyse the reasons behind the metabolic disorders

Course Outcomes

After completing this course, <br />? Students shall know the principles of catalysis in biological systems. <br />? Students will understand the reactions of metabolic pathways and their regulatory mechanisms.

Essential Reading

  • Nelson DL, Cox MM,, Lehninger Principles of Biochemistry. 6th edition, Freeman WH Publisher, , 2012, ISBN-10: 1429234148
  • Devasana T., Enzymology, Oxford University Press, New Delhi, , 2010, ISBN 9780198064435

Supplementary Reading

  • Deb AC,, Fundamentals of Biochemistry,, New Central Book Agency, Kolkata, , 10th edition (2011), ISBN-9788173811449
  • Voet Donald,, Biochemistry, John Wiley, New Jersey , 3rd edition (2008), ISBN-9780470233962