Course Details
Subject {L-T-P / C} : LS4407 : Cell Biology { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Prof. Sujit Kumar Bhutia
Syllabus
Cell and Cell Theory, Nucleus Structure and Organization, Endomembrane system - Protein Sorting and Transport, Mechanism of vesicular transport. Cyto-skeletal elements and Cell movement, Cell walls, Extra-cellular matrix, Cell-matrix interaction, Cell-cell communication, Cell adhesion and Junctions, Cell cycle and Division - CDKs and Cyclins, Mitosis, Meiosis and Cytokinesis, Regulation of oocyte meiosis, Programmed cell deaths, Cell Signaling - Direct and Indirect signaling, Signaling molecules and their receptors, Second messengers, Regulation of signaling pathways, Signaling Crosstalk and Feedback, Signal termination.
Course Objectives
- To understand the basic components of prokaryotic and eukaryotic cells, especially biomolecules, biological membranes, and organelles
- To learn protein sorting and transport in different organelles and the regulation
- To study cell maintenance and cell death and its physiological significance.
- To know the cellular mechanism underlying cell cycle, cell division and signaling.
Course Outcomes
Students should be able to differentiate various cellular structures, functions of cellular organelles, acquire knowledge about cell cycle and cellular trafficking.
Essential Reading
- Geoffrey M. Cooper and Robert E. Hausman, The Cell: A Molecular Approach,, The Cell: A Molecular Approach, Geoffrey M. Cooper and Robert E. Sinauer Associates, 7th Edition, 2015, , ISBN-10: 1605355402
- Bruce Alberts, Molecular Biology of the Cell, Garland Science, 6 edition, 2014, , ISBN-10: 0815344643
Supplementary Reading
- Harvey Lodish, Molecular Cell Biology, W. H. Freeman, 8th Edition, 2016 , ISBN-10: 1464187444
- Robert A. Weinberg, The Biology of Cancer, Garland Science publication, 2nd Edition, 2014 , ISBN-10: 0815345283