Course Details
Subject {L-T-P / C} : BM6331 : BioMEMS and Biosensor { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Dr. Earu Banoth
Syllabus
Introduction to MEMS and BioMEMS, Silicon microfabrication: materials for MEMS, Emergence, device and applications, Scaling issues. Microfabrication concept, types of microfabrication: Thin film deposition, Lithography, E-Beam Lithography, X-ray Lithography, Photolithography, Soft lithography, Etching, Wafer Bonding, Bulk Micromachining, Surface Micromachining, and LIGA process. Examples of MEMS, BioMEMS Devices.
Introduction to Sensors, Biosensors, Basic elements of Biosensors, Design, and fabrication of Biosensors, principles, and types of Biosensors, Applications of Biosensors, Materials for Biosensors, Concept of ‘Lab on a chip’, Components of lab-on-a chip: microsensor, lenses, heaters, sensors, etc. Minimally invasive biomedical microdevices, and LoC Future prospects. Overview of Biosensors, components of a biosensor, and design considerations. Biosensors for Health: Biosensors for diabetes, cardiovascular diseases, and cancer applications. Ion exchange membrane electrodes, enzyme electrodes, glucose sensors, immunosensors, Basic principles of MOSFET biosensors.
Course Objectives
- To aware the students about the fundamental principles of microsystems (MEMS and BioMEMS).
- To provide the concepts essential for designing lab-on-a-chip and Point-of-care devices for biomedical applications.
- To provide the concept of Biosensors, uses, design, and development for advanced research level so that students would be comfortable in higher studies.
- To Hands-on experience in in-house microfabrication (Photolithography) and Hands-on experience in fabricating simple LoC devices.
Course Outcomes
After completing the course, the students will be able to: <br /> <br />1. know the various MEMS design and fabrication techniques for Biosensors. Explore the concepts of BioMEMS & its application in healthcare. <br /> <br />2. Ability to identify basic requirements for a design application related to microfabrication and its techniques for biomedical systems. <br /> <br />3. To develop the skill to realize, build, and get hands-on experience fabricating simple LoC devices. <br /> <br />4. To analyze, compare, and appreciate the performance and merit of different lab-on-a-chip concepts, designs, and modes of work. <br /> <br />5. To know the different biosensors for biomedical applications, analyze, compare, and appreciate the performance and merit of different and point-of-care devices' concepts, importance, design, and work mode.
Essential Reading
- Tai Ran Hsu, MEMS and Microsystems Design and Manufacture, Tata McGraw Hill
- Wanjun Wang, Stephen A.Soper, BioMEMs: Technologies and Applications, CRC Press
Supplementary Reading
- Cooper J.M, Biosensors, Oxford publication
- Gerald A Urban, BioMEMS, Springer