Course Details
Subject {L-T-P / C} : BM6102 : Advanced Biomaterials { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Prof. Amit Biswas
Syllabus
Introduction to Biomaterials - Historical background and performance of biomaterials, Introduction to processing of biomaterials, Materials for orthopedic applications, New alloys for biomedical applications, Clinical application of Ni-Ti And Ni-Ti-Cu shape memory alloys, Corrosion and biocompatibility of orthopedic implants, Hard tissue and soft tissue–biomaterial interactions, Absorbable polymers for orthopedic repair, Osseous grafting materials for periodontal defects, cemented total hip and knee arthroplasties, Alumina and zirconia ceramics in hip surgery, Ceramic spine prostheses, Fundamentals of hydroxyapatite and related calcium phosphates, Micro macroporous biphasic calcium phosphate concept for bone reconstruction, Developments in Bone Cements, Characterization of Materials - Basics on physical, chemical and mechanical properties of materials, Standards for sterilistion of medical devices, In vitro and in vivo testing of biocompatibility, commercialization of implants - regulations and regulatory testing, The ethics of biomaterials and implants.
Course Objectives
- Provide post graduate-level foundation on current biomaterial principles
- Discuss the concepts of surfaces & interfaces in biomaterial interactions.
- Introduce new material and fabrication techniques for designing biomedical implants.
- Discuss cellular and molecular aspects of host responses to biomaterials.
Course Outcomes
1. Given a clinical problem, students will be able to select a range of potential biomaterials, including synthetic and/or biological strategies to repair lost tissue structure and function. <br />2. Given a biomaterial design problem, students will be able to outline all parameters needed to optimize the design. <br />3. Given a specific biomaterial, students will be able to identify the advantages and disadvantages of this material in terms of its material degradation and host response. <br />4. Given a specific organ/tissue system in need of reconstruction or regeneration, students will be able to identify appropriate candidate materials and an appropriate time frame of service-life. <br />5. Given a specific biomaterial, students will be able to identify the important biological responses of potential importance.
Essential Reading
- J. B. Park and R. S. Lakes, An Introduction to Biomaterials, Springer
- J.B Park, and J.D. Boonzino, Biomaterials: Principles and Application, CRC Press
Supplementary Reading
- J. Black, Biological Performance of materials, Taylor &Francis
- 4. B. D. Ratner, F. J. Schoen, A. S. Hoffman, and J. E. Lemons, Biomaterials Science: An introduction to Materials in medicine, Academic Press