Course Details
Subject {L-T-P / C} : BM2101 : Cell and Molecular Biology { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Prof. Nandini Sarkar
Syllabus
Introduction: Eukaryotic vs. Prokaryotic cell, Components of Eukaryotic Cell (cell membranes, subcellular organelles, cytoskeleton), Gene expression and regulation, Cellular membrane structure and function, Basic molecular genetic mechanism, Cell cycle and checkpoints in cell cycle regulation, Signalling at cell surface, Signalling pathways that control gene activity, Membrane transport, Protein trafficking, Cellular differentiation and stem cells, Regulation of cell cycle specific genes, Cellular aspects of cancer, Cellular, oncogenes and gene therapy.
Course Objectives
- To enable students understand the basics of cellular composition and functioning
- To enable the students understand the mechanism of gene expression, gene regulation and signal transduction pathways
- To enable the students understand the basics of stem cell research and cancer therapy
Course Outcomes
Students will be able to- <br />1) Have in-depth knowledge on cellular and sub-cellular components and their functions. <br />2) Understand different steps in the central dogma of molecular biology, enzymes involved in synthesis of DNA, RNA and protein. <br />3) Explain the nature of signals, sorting, SRP Receptor in the targeting of proteins to the endoplasmic reticulum and chaperone mediated protein folding. <br />4) Summarize transport of ions and small molecules across cell membranes <br />5) Have basic understanding of gene expression and regulation and application of various molecular biology and their impacts on society.
Essential Reading
- G. Karp, Cell and Molecular Biology: Concepts and Experiments, Wiley
- G. Nindl Waite, Applied Cell and Molecular Biology for Engineers, McGraw-Hill
Supplementary Reading
- B. Alberts, Molecular Biology of the Cell, Garland Science
- No thanks, No thanks, No thanks