Course Details
Subject {L-T-P / C} : BM3202 : Tissue Engineering { 3-1-0 / 4}
Subject Nature : Theory
Coordinator : Prof.(Ms.) Krishna Pramanik
Syllabus
Introduction to tissue engineering, Principles of engineering a tissue in vitro, biomaterials, scaffold: Design, fabrication, properties and characterization, cells and in vitro culture of cells, cell seeding, cell-biomaterial interaction: cell adhesion, migration, aggregation, Cell proliferation and differentiation, cell–scaffold construct & its characterization, Tissue microenvironment and bioreactor Cell signaling molecules, Ethical issues.
Course Objectives
- • To introduce students to the concepts, principles, and applications of tissue engineering for human tissue related diseases and/or damages through student-directed learning method
- To enable the student to design appropriate tissue-engineered scaffolds for various tissue engineering applications
- • To provide basic knowledge of stem cells, their expansion, and differentiation towards tissue formation by combining them with the tissue scaffold
- To enable the students to learn and apply suitable bioreactor systems for the production of tissue grafts or constructs.
Course Outcomes
The students will... <br />1. have the concept of tissue engineering and its application in human tissue health care. <br />2. be able to identify and develop biomaterials potential for specific tissue engineering application. <br />3. be able to apply tissue engineering principles and techniques to design and fabricate patient specific engineered matrices and their characterization. <br />4. have the basic knowledge of stem cells and their use in tissue regeneration in combination with tissue scaffold. <br />5. be able to produce tissue construct in-vitro by using bioreactor systems.
Essential Reading
- B. Palsson, S. Bhatia, Tissue Engineering,, Pearson Prentice Hall , 2003
- G. Vunjak-Novakovic, R. Ian Freshney,, Culture of Cells for Tissue Engineering,, WIS , 2006
Supplementary Reading
- B. Palsson, J.A. Hubbell, R. Plonseyand J.D. Bronzino,, Tissue Engineering, CRC- Taylor&Francis
- R. P. Lanza, R. Langerand W. L. Chick,, Principles of tissue engineering,, Academic press, , 1997