Module-I
Introduction: A brief review on current clinical treatment of tissue &/or Organ defect. Concept of Tissue engineering, Engineering principles involved in TE, Prospects and challenges

Module-II
Biomaterials for TE: Biomaterial Classification, Ideal biomaterials for TE, Biomaterial processing and properties

Module-III
Scaffold: Concept and functions, Scaffold Properties-physico-chemical-mechanical and biological, Scaffold Design and Fabrication- conventional and advanced techniques for 2D and 3D design, Scaffold Characterization techniques

Module-IV
Stem Cells: Basics of stem cells- Types, classification, properties and sources, Stem Cell Culturing/ Expansion, Stem Cell Differentiation, Stem cell Characterisation, Ethical issues

Module-V
Cell- scaffold integration: Introduction, cell seeding techniques, Bioreactors for Tissue Engineering, Cell-scaffold interaction- cell adhesion, cell proliferation, cell migration and cell agglomeration, Assessment of tissue construct, Ethical and regulatory issues.

• To introduce students to the concepts, principles, and applications of tissue engineering for human tissue related diseases and/or damages through student-directed learning method

To enable the student to design appropriate tissue-engineered scaffolds for various tissue engineering applications

• To provide basic knowledge of stem cells, their expansion, and differentiation towards tissue formation by combining them with the tissue scaffold

To enable the students to learn and apply suitable bioreactor systems for the production of tissue grafts or constructs.

The students will...
1. have the concept of tissue engineering and its application in human tissue health care.
2. be able to identify and develop biomaterials potential for specific tissue engineering application.
3. be able to apply tissue engineering principles and techniques to design and fabricate patient specific engineered matrices and their characterization.
4. have the basic knowledge of stem cells and their use in tissue regeneration in combination with tissue scaffold.
5. be able to produce tissue construct in-vitro by using bioreactor systems.

B. Palsson, S. Bhatia, Tissue Engineering,, Pearson Prentice Hall , 2003

G. Vunjak-Novakovic, R. Ian Freshney,, Culture of Cells for Tissue Engineering,, WIS , 2006

B. Palsson, J.A. Hubbell, R. Plonseyand J.D. Bronzino,, Tissue Engineering, CRC- Taylor&Francis

R. P. Lanza, R. Langerand W. L. Chick,, Principles of tissue engineering,, Academic press, , 1997