Course Details
Subject {L-T-P / C} : BM3201 : Biomaterials { 3-1-0 / 4}
Subject Nature : Theory
Coordinator : Prof. Devendra Verma
Syllabus
Properties of materials, Structure of solids, Introduction of biomaterials, Metallic implant materials: Austenitic stainless steel, Co-based alloys, Titanium-based alloys and Dental alloys, Degradation processes on metallic surfaces, Ceramics implant materials: Glasses and Glass-ceramics, Alumina, Zirconia and Calcium phosphate, Bioresorbable and bioactive ceramics, Polymeric implant materials: Inert polymers, Natural polymers, Bioactive polymers, Biodegradable polymers, Composite implant materials: Mechanics of composite, Different composite biomaterials, Application of composite biomaterials.
Structure-property relationships of biological materials, Tissue response to implant surface, Softtissue replacement: Skin, Sutures, Maxillofacial implants and Blood interfacing implants, Hard tissue replacement: Long bone repair-wires, pins, screws, fractures plates, intramedullary devices, joint replacement-knee and hip joint, dental restorations and spinal implants.
Characterization of biomaterials: Physical and physicochemical surface characterization: Mechanical, Optical and Electrochemical characterization. Biocompatibility and Biological tests. Infection and sterilization.
Course Objectives
- The students will gain an appreciation for the role of biomaterials in modern medical science.
- The students will understand the fundamental concepts of biomaterials and gain knowledge of the structure of solids, bulk properties of materials, surface properties and characterization.
- The students will be able to identify design requirements and select types of biomaterials for specific biomedical applications.
- The students will understand the tissue response depending on the properties of the biomaterials applied.
Course Outcomes
1. Demonstrate a broad knowledge of different types of biomaterials, including metals, polymers, ceramics, composites and nanomaterials, and their use in typical biomedical devices and clinical applications. <br />2. Apply fundamental materials science and biology concepts to solve biomaterials-related problems. <br />3. Read the scientific literature critically on biomaterials, <br />4. Develop new solutions to problems with biomaterials presently used by the medical profession and formulate these ideas into a written research paper and oral presentation. <br />5. Evaluate structure-function relationship in a broad range of biomaterials. <br />6. Demonstrate understanding of tissue response to different types of materials <br />7. Demonstrate a detailed understanding of the design requirements of biomedical devices specific to various tissues and organs.
Essential Reading
- J. Park, Biomaterials, An Introduction to Biomaterials, Springer, 2012
- J.B Park, and J.D. Boonzino, Biomaterials: Principles and Application, CRC Press, 2002
Supplementary Reading
- J. B. Park and R. S. Lakes, An Introduction to Biomaterials, Springer, 2007
- 4. B. D. Ratner, F. J. Schoen, A. S. Hoffman, and J. E. Lemons, Biomaterials Science: An introduction to Materials in medicine,, Academic Press, 2012 , 3rd edition