Course Details
Subject {L-T-P / C} : BM2504 : Transport Processes in Biological System { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Dr. Anju R. Babu
Syllabus
Introduction to fluid mechanics, properties of fluids, Viscosity, Continuity equation, Euler’s equation, Bernoulli’s equation, application of Bernoulli’s equation, Navier and Stokes equations, Hagan-Poiseuille equation. Physiological properties of biological fluids, Fluid flow in the circulation, Blood-tissue transport of solutes in the microcirculation, and Membrane transport processes. Introduction to fundamental principles of mass transport and its application to biological systems. Microcirculation, Starling’s law, Rouleaux Effect, Segre–Silberberg effect, Fähraeus-Lindqvist effect, Fick's Law of Diffusion. Pulmonary Gas Exchange, Alveolar Gas Equation, Transport pathways across the human Blood-brain barrier. Heat transfer in biological systems, Counter heat exchange, Bioheat Equation. Pharmacokinetics, Transdermal drug delivery system, Drug distribution patterns.
Course Objectives
- To know the various fluid mechanics concepts and applications in biological process
- To understand the transport phenomenon at the molecular, cellular, tissue, and organism level
- To introduce the applicability of principles of heat and mass transfer in biological systems
Course Outcomes
1. Gain the fundamental concepts of mass transfer, in the biological transport processes <br />2. Apply fluid mechanics principles to the solve problems in the bio-transport process <br />3. Gain knowledge in the transport process of liquid and gas in the biological system <br />4. Understand the applicability of heat transfer in the biological system <br />5. Familiarise with the basic concepts of drug pharmacokinetics
Essential Reading
- Arthur T. Johnson, Biological Process Engineering, John Wiley, New York, 1999
- C. G. Geankoplis, Transport Processes and Unit Operations, Allyn and Bacon, Boston, 1983.
Supplementary Reading
- Frank P. Incropera and David P. DeWitt,, Fundamentals of Heat and Mass Transfer:, John Wiley & Sons 5th edition 2006.
- D. J. Haynie,, Biological thermodynamics, Cambridge, 2008.