Course Details
Subject {L-T-P / C} : BM6638 : OMICS in Biotechnology { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Prof. Angana Sarkar
Syllabus
Overview and general principles of omics technologies in biotechnology, Omics approaches: Genomics, Proteomics, Transcriptomics and Metabolomics, Meta-omics (genomics, proteomics, transcriptomics, metabolomics) and Functional omics for discovery of novel organisms, enzymes, value added products etc., Application of Omics in different fields of biotechnology including agriculture, environment, pharmaceuticals, medicine, forensic etc. Omic tools (DNA-sequencing, Genome Sequencing, Next Generation Sequencing(NGS) methods, gene expression microarray, MS-based proteomics, NMR-based metabolomics),ranscription factor binding sites,RNA-Seq, Microarrays, Regulatory RNAs: small or large, Computational prediction of miRNA target genes, RNA Darkmatter, SDS PAGE, 2D PAGE , Liquid chromatography , Mass Spectrometry (ESI and MALDI) ,Protein identification by peptide mass fingerprinting, Capillary electrophoresis, Gas chromatography, Electrochemical detector,Computational techniques in data integration and big-data handling inGenome Annotation, Omics projects worldwide.
Course Objectives
- To grow knowledge regarding the modern application of molecular tools in real life problems
Course Outcomes
Develop knowledge on the basics of omics and their versatile applications. <br />Integration of omics approaches for improvement of life. <br />Technical skills and knowledge development on versatile techniques in omics
Essential Reading
- DebmalyaBarh Vasco Azevedo, Omics Technologies and Bio-engineering, 1st Edition, Volume 1: Towards Improving Quality of Life, Academic Press
- Wittmann, C. and Lee, S.Y. eds, Systems metabolic engineering, Springer Science & Business Media
Supplementary Reading
- Barh, D., Zambare, V. and Azevedo, V. eds, Omics: applications in biomedical, agricultural, and environmental sciences, CRC Press
- Kihara, D. ed, Protein function prediction for omics era, Springer Science & Business Media