Course Details
Subject {L-T-P / C} : BM6501 : Bioprocess Engineering { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Prof. Kasturi Dutta
Syllabus
Introduction: Fermentation processes general requirements of fermentation processes – An overview of aerobic and anaerobic fermentation processes and their application in industry -
Medium requirements for fermentation processes - examples of simple and complex media Design and usage of commercial media for industrial fermentation. Sterilization: Thermal death kinetics of micro-organisms - Batch and Continuous Heat-Sterilization of liquid Media, Filter Sterilization of Liquid Media and Air.Stoichiometry and Kinetics of substrate utilization and Biomass and product formation in cell cultures Plasmid stability in recombinant cell culturesBioreactor and product recovery operations: Operating considerations for bioreactors for suspension and immobilized cultures: batch, fed batch and continuous operation Selection, scale-up, operation of bioreactors Enzyme technology, Enzymes: Classification and properties Applied enzyme catalysis - Kinetics of enzyme catalytic reactions
Course Objectives
- To have complete idea for developing bioprocess for particular microbial product.
Course Outcomes
1. Students will have complete idea for developing bioprocess for particular microbial product. <br />2. This will help to have the concept to enhance the productivity of microbial products <br />3. Scale up of products from laboratory to large scale.
Essential Reading
- M. L Shular and F. Kargi, Bio-process engineering Basic Concepts, Prentice Hall
- J. E. Bailey and D. F. Ollis, Biochemical Engineering Fundamentals, McGraw-Hill Publishing Co. New York
Supplementary Reading
- P. Stanbury, A. Whitakar and S. J. Hall, Principles of Fermentation Technology, Elsevier-Pergamon Press
- P. M. Doran, Bioprocess Engineering principles, Academic press