EXPERTISE INFORMATION
Research Group
- Biophysical Sciences
Areas of Interest
- Protein conformational dynamics (folding/misfolding) Protein-protein/nanoparticle/metal ion interactions Nanoscale biophysics
42
PUBLICATIONS6
SPONSORED PROJECTS13
DOCTORAL STUDENTSPERSONAL INFORMATION
Suman Jha
Associate Professor
Life Science
Room Number: MN-344
Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India - 769008
2009
Ph.D.
Biophysical SciencesTechnical University of Dortmund / Max-Planck Institute For Molecular Physiology
2005
M.Sc
Protein Biophysics / BiotechnologyJawaharlal Nehru University
2002
B.Sc
ChemistryKirrori Mal College / Delhi University
Teaching Experience
- Biophysics / Biophysical Tools for research in biological sciences, National Institute of Technology Rourkela, 05 Sep 2011 - to date
Post Doctoral Research Experience
- Protein Biophysics / Protein Folding, University of Connecticut, 21 Mar 2010 - 30 Aug 2011
Optimizing znonp-insulin interaction interface in order to optimize insulin formulation. ICMR
- Principal Investigator
- 36
- Completed Sponsored
Evaluation of alpha-synuclein aggregation propensity on interaction with varying zinc oxide nanoparticles interfaces. DST,ODISHA
- Principal Investigator
- 36
- Completed Sponsored
Nanoparticle based approach to enhance the AMP efficacy against AMP resistant bacteria DBT
- Principal Investigator
- 36
- Completed Sponsored
Nanoparticle: A boon or bane for human IAPP/ pro IAPP INSPIRE,DST,GOI
- Principal Investigator
- 60
- Completed Sponsored
Deciphering role of cancer stem cells to therapy resistance in oral cancer SERB
- Co-Investigator
- 36
- Completed Sponsored
Conformational Amyloidogenic & Cytotoxic propensity of Human Proiapp DBT
- Principal Investigator
- 36
- Completed Sponsored
Total Publications: 42
K. K. Yadav, M. Ojha, R. Pariary, M. Arakha, A. Bhunia, and S. Jha,"Zinc oxide nanoparticle interface moderation with tyrosine and tryptophan reverses the pro-amyloidogenic property of the particle", Biochimie, vol.193, pp.64-77, Elsevier, February 2022, 10.1016/j.biochi.2021.10.011 Article
S. Asthana, D. Bhattacharyya, S. Kumari, P. S. Nayak, M. Saleem, A. Bhunia, and S. Jha,"Interaction with zinc oxide nanoparticle kinetically traps a-synuclein fibrillation into off-pathway non-toxic intermediates", International journal of biological macromolecules, vol.150, pp.68-79, Elsevier, May 2022, 10.1016/j.ijbiomac.2020.01.269 Article
S. Asthana, H. Z, P. S. Nayak, J. Roy, A. N. Jha, B. Mallick, and S. Jha,"Insulin adsorption onto zinc oxide nanoparticle mediates conformational rearrangement into amyloid-like structure with an enhanced cytotoxic propensity", B.B.A. General Subjects, vol.1863, pp.153-166, Elsevier, January 2019 Article
P. S. Nayak, S. M. Borah, H. Gogoi, S. Asthana, R. Bhatnagar, A. N. Jha, and S. Jha,"Lactoferrin adsorption onto silver nanoparticle interface: implications of corona on protein conformation, nanoparticle cytotoxicity and the formulation adjuvanticity", Chemical Engineering Journal, vol.361, pp.470-484, Elsevier 2019, 10.1016/j.cej.2018.12.084 Article
M. Arakha, . Pal, D. Samantarrai, T. Panigrahi, B. Mallick, K. Pramanik, B. Mallick, and S. Jha,"Antimicrobial activity of iron oxide nanoparticle upon modulation of nanoparticle-bacteria interface", Scientific Reports, vol.5, pp.14813, Nature publishing, October 2015, 10.1038/srep14813 Article
- LS100 : Biology {Theory}
- LS1001 : Biology {Theory}
- LS201 : Basic Biochemistry {Theory}
- LS201 : Biochemistry {Theory}
- LS304 : Bioinstrumentation {Theory}
- LS307 : Biophysics {Theory}
- LS3302 : Bioinstrumentation {Theory}
- LS3303 : Biophysics {Theory}
- LS411 : Biophysics {Theory}
- LS423 : Advanced Techniques {Theory}
- LS427 : Advanced Techniques {Theory}
- LS4301 : Bioanalytical Techniques {Theory}
- LS440 : Physical Sciences and Instrumentation {Theory}
- LS504 : Bioanalytical Techniques {Theory}
- LS582 : Molecular Biophysics {Theory}
- LS6009 : Molecular Biophysics {Theory}
- LS609 : Molecular Biophysics {Theory}
- LS271 : Biochemistry Laboratory {Practical}
- LS3094 : Life Science Laboratory- IV {Practical}
- LS372 : Bioinstrumentation Laboratory {Practical}
- LS4391 : Bioanalytical Techniques Laboratory {Practical}
- LS473 : Biotechnology Laboratory {Practical}
- LS478 : Computational Nucleic acids and Proteins Laboratory {Practical}
- LS571 : Advanced Techniques Laboratory {Practical}
Ph.D. Students [13]
Effects of Photocatalytic Nanoparticle Interfaces on Biological Membranes and Biomacromolecules
Manoranjan ArakhaEnrolled: Oct 2012Graduated : 2016Supervisor
Nanoparticle Functionalization: Implications in Corona-modulated Biological Applications
Parth Sarathi NayakEnrolled: Jul 2013Graduated : 2018Supervisor
The Effects of Zinc Oxide Nanoparticle Interface on Conformational Dynamics of Protein Models from Different Structural Hierarchies
Shreyasi AsthanaEnrolled: Oct 2013Graduated : 2018Supervisor
Modulation of different proteins' conformational dynamics in the presence of ZnO nanoparticles with varying surface properties
Kanti Kusum YadavEnrolled: Aug 2012Graduated : 2019Supervisor
Perturbations of Cellular Model Membranes Induced by Membrane-Interacting Model Peptide, Protein and Proteoliposome
Ashutosh PrinceEnrolled: Jul 2014Graduated : 2019Co-Supervisor
Study on Membrane Parameters Involved in ZnONP Penetration and Amyloid Beta Interaction in Neurodegeneration
Anuj Satish TiwariEnrolled: Jul 2015Graduated : 2021Co-Supervisor
Biological implications of biofabricated nanoparticles.
Kumari SubhamEnrolled: Jul 2019ContinuingSupervisor
protein biology.
Sonali MohantyEnrolled: Jul 2019ContinuingSupervisor
protein biology
Monalisha OjhaEnrolled: Jul 2019ContinuingSupervisor
Biological implications of biofabricated nanoparticles.
Sonali JenaEnrolled: Jul 2019ContinuingSupervisor
Structural biology, nanotechnology, cancer biology
Harshit KalraEnrolled: Oct 2021ContinuingSupervisor
Screening of plant and microbe based compounds with potential to moderate amyloidogenic propensity of Insulin and alpha-Synuclein
Mohita KarmiEnrolled: Jul 2023ContinuingSupervisor
Screening of different herbal phytochemicals role in circulatory protein amyloidosis.
Devikrupa SinghEnrolled: Jan 2024ContinuingSupervisor