National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

An Institute of National Importance

Faculty Profile

EXPERTISE INFORMATION

Research Group
  • Immunology and Molecular Medicine
Areas of Interest
  • Host-pathogen interaction in M. tuberculosis infection, Autophagy, Microbial Immunology, Innate and adaptive immunity in tuberculosis

Rohan Dhiman Associate Professor & Registrar

Life Science

dhimanr@nitrkl.ac.in

0661 - 246 2780

68

PUBLICATIONS

7

SPONSORED PROJECTS

9

DOCTORAL STUDENTS

3

CONTINUING EDUCATION

PERSONAL INFORMATION

Rohan Dhiman

Associate Professor

Life Science

Room Number: MN-246

Department of Life Science, National Institute of Technology Rourkela, Sundargarh, Odisha, India - 769008

Ph.D. (Institute of Microbial Technology, Chandigarh)

To delineate the survival strategy of mycobacteria through antigenic determinants by inhibiting autophagy via miRNA and its significance in host directed therapy. DBT
  • Principal Investigator
  • 36
  • Running   Sponsored
Involvement of bacterial cytoskeleton in morphogenesis during biofilm development for xenobiotic degradation. BRNS
  • Co-Investigator
  • 36
  • Running   Sponsored
Identification of novel autophagy modulators to augment host directed therapies again mycobacteria. Science & Technology Department,Govt Of Odisha
  • Principal Investigator
  • 36
  • Running   Sponsored
To decipher the epigenietic regulatory mechanism(s) of SOX2 gene in human prostate cancer and self renewal of cancer stem cell. SERB
  • Co-Investigator
  • 36
  • Completed   Sponsored
Soybean lectins and their antimycobacterial role by regulating autophagy SERB
  • Principal Investigator
  • 36
  • Completed   Sponsored
To study the antimycobacterial role of calcium ionophores by inducing autophagy of mycobacteria infected macrophages DST
  • Principal Investigator
  • 60
  • Completed   Sponsored
To study the effect of major immunodominant antigens of mycobacteria on calcimycin induced autophagy in infected macrophages SERB
  • Principal Investigator
  • 36
  • Completed   Sponsored

Total Publications: 68

A. Mishra, A. Behura, A. Kumar, L. Naik, A. Swain, M. Das, S. S. Sarangi, P. Dokania, V. Dirisala, S. K. Bhutia, A. Mishra, R. Singh, and R. Dhiman,"P2X7 receptor in multifaceted cellular signaling and its relevance as a potential therapeutic target in different diseases", European Journal of Pharmacology, vol.906, pp.174235, Elsevier 2021, 10.1016/j.ejphar.2021.174235       Article

A. Behura, M. Das, A. Kumar, L. Naik, A. Mishra, D. Manna, S. Patel, A. Mishra, R. Singh, and R. Dhiman,"ESAT-6 impedes IL-18 mediated phagosome lysosome fusion via microRNA-30a upon Calcimycin treatment in mycobacteria infected macrophages", International Immunopharmacology, vol.101, no.108319, Elsevier, November 2021, 10.1016/j.intimp.2021.108319       Article

A. Kumar, L. Naik, S. Patel, M. Das, Dev. K. Nayak, A. Mishra, A. Mishra, R. Singh, A. Behura, and R. Dhiman,"Ac-93253 inhibits intracellular growth of mycobacteria in human macrophages by inducing apoptosis in mitochondrial-dependent manner", Biochimica et Biophysica Acta - General Subjects, vol.1867, no.9, pp.13, Elsevier, September 2023, 10.1016/j.bbagen.2023.130425       Article

A. Behura, L. Naik, S. Patel, M. Das, A. Kumar, A. Mishra, Dev. K. Nayak, D. Manna, A. Mishra, and R. Dhiman,"Involvement of epigenetics in affecting host immunity during SARS-CoV-2 infection", Biochimica et Biophysica Acta - Molecular Basis of Disease, vol.1869, no.166634, pp.13, Elsevier, March 2023, 10.1016/j.bbadis.2022.166634       Article

L. Naik, S. Patel, A. Kumar, A. Ghosh, A. Mishra, M. Das, Dev. K. Nayak, S. Saha, A. Mishra, R. Singh, A. Behura, and R. Dhiman,"4-(Benzyloxy)phenol-induced p53 exhibits antimycobacterial response triggering phagosome-lysosome fusion through ROS-dependent intracellular Ca2+ pathway in THP-1 cells", Microbiological Research, vol.282, no.127664, Elsevier 2024, 10.1016/j.micres.2024.127664       Article

Host-pathogen interaction: present and future perspective (Online) Life Science (Conference)
Host-pathogen interaction: present and future perspective (Online) Life Science (Conference)
Techniques to Understand Autophagic Processes in Mammalian Systems (TUAPMS) Life Science (Workshop)

  • LS100 : Biology {Theory}
  • LS1001 : Biology {Theory}
  • LS204 : Plant Science {Theory}
  • LS2403 : Plant Science {Theory}
  • LS303 : Genetics {Theory}
  • LS311 : Cell and Cellular Techniques {Theory}
  • LS3405 : Genetics {Theory}
  • LS6002 : Advanced Immunology {Theory}
  • LS602 : Advanced Immunology {Theory}
  • LS2092 : Life Science Laboratory- II {Practical}
  • LS274 : Plant Science Laboratory {Practical}
  • LS3093 : Life Science Laboratory- III {Practical}

Ph.D. Students [9]
Modulation of Autophagy and its Effect on Intracellular Mycobacteria by Calcimycin
Shradha Mawatwal
Enrolled: Jan 2015
Graduated :  2018
Supervisor
Evolutionary Adaptations and Host Immune Modulation by Salmonella Typhimurium
Diana Pradhan
Enrolled: Jul 2014
Graduated :  2019
Co-Supervisor
Mechanistic Insight on the Role of ESAT-6 in Modulating Host Defensive Pathways through MicroRNA-30a in Mycobacteria Infected Macrophages
Assirbad Behura
Enrolled: Jul 2016
Graduated :  2021
Supervisor
Stimulation of Autophagy by Soybean Lectin (SBL) and Its Antimycobacterial Response in Human Macrophages
Abtar Mishra
Enrolled: Jan 2017
Graduated :  2022
Supervisor
Understanding the Role of Ac-93253 Iodide in Apoptosis as an Anti-mycobacterial Response in Macrophages
Ashish Kumar
Enrolled: Jul 2018
Graduated :  2023
Supervisor
Host pathogen interaction in Tuberculosis and role of autophagy in antimycobacterial response
Lincoln Naik
Enrolled: Jul 2019
Continuing
Supervisor
Molecular Biology,Immunology,Cell Biology,Cancer Biology,Micro Biology
Salina Patel
Enrolled: Sep 2020
Continuing
Supervisor
MICROBIOLOGY
Mousumi Das
Enrolled: Sep 2020
Continuing
Supervisor
Mycobacterial Immunology and host-directed therapy
Dev Kiran Nayak
Enrolled: Feb 2022
Continuing
Supervisor

Memberships / Fellowships
  • The Indian Science Congress Association, Indian Immunology Society,