Course Details
Subject {L-T-P / C} : BM6132 : Advanced Tissue Engineering { 3-0-0 / 3}
Subject Nature : Theory
Coordinator : Prof. Devendra Verma
Syllabus
Introduction to mammalian cell, stem cells, scaffolds and signalling molecules. Cell adhesion and cell migration, extracellular matrix, cell aggregates, designing scaffolds, fabrication of scaffolds, cell-materials interactions, growth factors and their role in tissue genesis, delivery of growth factors, types of bioreactors used for tissue engineering, design & production of functional tissue units, Clinical applications & regulatory issues.
Course Objectives
- Learn the fundamental principles that serve as the scientific basis for understanding the interactions of biological molecules and cells with biomaterials employed for tissue engineering applications.
- Able to design a Scaffold considering the biodegradability and main issues of biocompatibility including toxicity.
- Understand the role of each component of tissue engineering
Course Outcomes
1. Design tissue-specific scaffolds for regeneration of organs and tissues <br />2. Design a Scaffold considering the biodegradability and main issues of biocompatibility including toxicity.
Essential Reading
- Clemens A. van Blitterswijk and Jan De Boer, Tissue Engineering, Academic Press , Second Edition 2015
- B. Palsson, S. Bhatia, Tissue Engineering, Pearson Education India , First edition 2016
Supplementary Reading
- R. P. Lanza, R. Langer and W. L. Chick, Principles of tissue engineering, Academic press , 4th Edition, 2013
- Peter X. Ma, Biomaterials and Regenerative Medicine, Cambridge University Press , 2014