Syllabus

A) Basic history concepts of development : History of developmental biology, Potency, commitment, specification, induction, competence, determination and differentiation morphogenetic gradients cell fate and cell lineages stem cells genomic equivalence and the cytoplasmic determinants imprinting mutants and transgenics in analysis of development, weisman and Roux experiment, role of model organism in development, morphogenesis, pattern formation
B) Gametogenesis, fertilization and early development: Production of gametes, cell surface molecules in sperm-egg recognition in animals embryo sac development and double fertilization in plants zygote formation, cleavage, blastula formation, embryonic fields, gastrulation and formation of germ layers in animals embryogenesis, polarity, establishment of symmetry in plants seed formation and germination.
C) Morphogenesis and organogenesis in animals : Developmental cycle, Cell aggregation and differentiation in Dictyostelium axes and pattern formation in Drosophila, amphibia, mouse, C.elegans and chick organogenesis – vulva formation in Caenorhabditis elegans, eye lens induction, limb development and regeneration in vertebrates differentiation of neurons, post embryonic development- larval formation, metamorphosis environmental regulation of normal development sex determination.
D) Morphogenesis and organogenesis in plants: Organization of shoot and root apical meristem shoot and root development leaf development and phyllotaxy transition to flowering, floral meristems and floral development in Arabidopsis genes regulating different parts of flower circadian rhythm and it’s effect on development.

Introduce the concept of development in different animals

How development is regulated by different genes and transcription factors

How development proceed in different phylum

Different parameters that regulate the development

On completion of the course, the students shall be able to
CO 1: acquire knowledge on history of developmental biology and different experiments conducted to come up with the modern concepts of developmental biology
CO 2: understand the role of genes and transcription factors in the process of development
CO 3: gain knowledge of HOX genes and miroRNA regulating the developmental process
CO 4: comparison of molecular mechanism of development in different phyla
CO 5: different exogenous and endogenous parameter that regulate the process of development

Lewis Wolpert, Rosa Beddington, Thomas Jessell, Peter Lawrence, Elliot Meyerowitz, Jim Smith, Principles of Development, Elsevier Science under Auspices of Society for Developmental Biology

Gilbert, Scott F, Developmental Biology, ?Sinauer Associates Inc

SLACK, Essential Developmental Biology, JOHN WILEY

Michael J.F. Barresi , Scott F. Gilbert, Developmental Biology, Wiley Blakwel

Development

European journal of developmental biology