National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

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Syllabus

Course Details

Subject {L-T-P / C} : LS4409 : Developmental Biology { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Monalisa Mishra

Syllabus

Module 1 :

History of developmental biology, Potency, commitment, specification, induction, competence, determination, differentiation morphogenetic gradients cell fate and cell lineages stem cells, role of model organism in development, morphogenesis, pattern formation

Module 2 :

Gametogenesis, fertilization and early development: Production of gametes, cell surface molecules in sperm-egg recognition in animals, cleavage, blastula, gastrulation, formation of germ layers in animals, embryogenesis, polarity, establishment of symmetry

Module 3 :

Weisman and Roux experiment, Developmental cycle, Cell aggregation and differentiation in Dictyostelium axes and pattern formation in Drosophila, Amphibia, Mouse, C.elegans and Chick organogenesis

Module 4 :

Post embryonic development, larva formation, metamorphosis and environmental regulation of normal development sex determination.

Course Objective

1 .

Introduce the concept of development in different animals

2 .

How development is regulated by different genes and transcription factors

3 .

How development proceed in different phylum

4 .

Different parameters that regulate the development

Course Outcome

1 .

On completion of the course, the students shall be able to
CO 1: Acquire knowledge on history of developmental biology and different experiments conducted to come up with the modern concepts of developmental biology
CO 2: Understand the role of genes and transcription factors in the process of development
CO 3: Gain knowledge of HOX genes and miroRNA regulating the developmental process
CO 4: Comparison of molecular mechanism of development in different phyla
CO 5: Different exogenous and endogenous parameter that regulate the process of development

Essential Reading

1 .

Lewis Wolpert, Rosa Beddington, Thomas Jessell, Peter Lawrence, Elliot Meyerowitz, Jim Smith, Principles of Development, Elsevier Science under Auspices of Society for Developmental Biology

2 .

Gilbert, Scott F, Developmental Biology, ?Sinauer Associates Inc

Supplementary Reading

1 .

SLACK, Essential Developmental Biology, JOHN WILEY

2 .

Michael J.F. Barresi , Scott F. Gilbert, Developmental Biology, Wiley Blakwel

Journal and Conferences

1 .

Development

2 .

European journal of developmental biology