National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

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Syllabus

Course Details

Subject {L-T-P / C} : LS4407 : Cell Biology { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Sujit Kumar Bhutia

Syllabus

Module 1 :

Cell and Cell Theory, Nucleus Structure and Organization, Endomembrane system - Protein Sorting and Transport, Mechanism of vesicular transport. Cyto-skeletal elements and Cell movement, Cell walls, Extra-cellular matrix, Cell-matrix interaction, Cell-cell communication, Cell adhesion and Junctions, Cell cycle and Division - CDKs and Cyclins, Mitosis, Meiosis and Cytokinesis, Regulation of oocyte meiosis, Programmed cell deaths, Cell Signaling - Direct and Indirect signaling, Signaling molecules and their receptors, Second messengers, Regulation of signaling pathways, Signaling Crosstalk and Feedback, Signal termination.

Course Objective

1 .

To understand the basic components of prokaryotic and eukaryotic cells, especially biomolecules, biological membranes, and organelles

2 .

To learn protein sorting and transport in different organelles and the regulation

3 .

To study cell maintenance and cell death and its physiological significance.

4 .

To know the cellular mechanism underlying cell cycle, cell division and signaling.

Course Outcome

1 .

Students should be able to differentiate various cellular structures, functions of cellular organelles, acquire knowledge about cell cycle and cellular trafficking.

Essential Reading

1 .

Geoffrey M. Cooper and Robert E. Hausman, The Cell: A Molecular Approach,, The Cell: A Molecular Approach, Geoffrey M. Cooper and Robert E. Sinauer Associates, 7th Edition, 2015, , ISBN-10: 1605355402

2 .

Bruce Alberts, Molecular Biology of the Cell, Garland Science, 6 edition, 2014, , ISBN-10: 0815344643

Supplementary Reading

1 .

Harvey Lodish, Molecular Cell Biology, W. H. Freeman, 8th Edition, 2016 , ISBN-10: 1464187444

2 .

Robert A. Weinberg, The Biology of Cancer, Garland Science publication, 2nd Edition, 2014 , ISBN-10: 0815345283