Syllabus

UV-visible Absorption Spectroscopy and its Applications: UV-Vis Spectrophotometer and its components. Quantification of analytes (Single/Multi-component Analysis), Job’s plot (M:L stoichiometry), pKa determination, Circular Dichroism (CD) and its applications. (6-7 hours)

Elemental Analysis (Atomic Spectroscopic Techniques): Atomic absorption/emission spectroscopy (AAS/AES), X-ray fluorescence (XRF), Inductively coupled plasma (ICP-MS/OES). (4-5 hours)

Electrochemical Analysis: Electrode potential, Nernst equation, Polarography, Determining E1/2 by Redox Titration and Spectroelectrochemistry, Cyclic Voltammetry (CV) and its applications (Determining E1/2, diffusion coefficient and no. of e-/H+ involvement), Potentiometry: pH measurement & Ion-selective electrode, Amperometry: Oximetry. (8-9 hours)

Calorimetric methods of analysis: Differential Scanning Calorimetry (DSC),
Isothermal Titration Calorimetry (ITC). (3 hours)

Chromatography & Electrophoresis: SEC/IEC, Electrophoresis (4-5 hours)

Special Techniques: @@@........
Light Scattering: DLS/MALS, Nephelometry/Turbidimetry, AUC (3-4 hours)

Mass Spectrometry: Conventional vs. Electro-spray Ionisation (ESI-MS). (2-3 hours)

Mossbauer Spectroscopy: Oxidation-state and Spin-state (2-3 hours)

MRI and EPR: Analysis/Quantification of paramagnetic species (4 hours)

Flow-methods: Stopped-flow and continuous flow (2 hours)

To educate different types of analytical techniques exercised in chemistry.

To understand the dynamic range and Pros/Cons of each technique for the proper selection.

To appreciate the error and confidence limit to better present data.

1) Students will be familiar of different types of analytical techniques exercised in chemistry.
2) Students will be able to learn both theoretical and instrumental aspects of various detection
processes.
3. The course will help the student to select the appropriate technique.
4. The course will help the student to present the data in a better/statistically correct way.
5. The course will help to understand experimental findings reported in the literature/paper.

Skoog, Holler, & Crouch, Principles of Instrumental Analysis, 7th Edn., Cengage Learning , 2016

Daniel. C. Harris, Quantitative Chemical Analysis, W.H. Freeman &Co. , 2010

Skoog, West, Holler, & Crouch, Fundamentals of Analytical Chemistry, Saunders College Pub , 2007

G.W. Ewing, Instrumental Methods of Analysis, McGraw-Hill College 5th edition , 2009

Journal of Chemical Education

Analytical Chemistry (ACS), Analyst (RSC).