National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

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Syllabus

Course Details

Subject {L-T-P / C} : CY4104 : Spectroscopic Methods of Analysis { 3-1-0 / 4}

Subject Nature : Theory

Coordinator : Bimalendu Adhikari

Syllabus

Module 1 :

Electromagnetic radiations: Types of molecular energy and molecular spectroscopy
Infrared Spectroscopy: Basic theory, instrumentation and application to functional group determination. UV-Visible Spectroscopy: Basic concepts, instrumentation and applications Mass Spectrometry: Principle, Instrumentation and applications, Fragmentation pattern of organic compounds, McLafferty rearrangement NMR Spectroscopy: Basic principles, Chemical shift, Spin-Spin Coupling, Coupling Constant, NOE, 13C NMR, DEPT NMR, heteronuclear coupling, Pulse NMR spectroscopy and techniques, relaxation time and their importance, determination of relaxation times, Temperature dependent NMR and molecular dynamics, Elementary ideas on 2D NMR spectroscopy (COSY, NOESY, HMQC, HSQC, HMBC), Extension to other nuclei (19F, 31P etc).
Structure elucidation of Organic Compounds: Use of spectroscopic techniques for structure determination and other applications.
Optical rotatory dispersion and Circular dichroism: Definition, deduction of absolute configuration, octant rule for ketones.

Course Objective

1 .

Students will learn basic spectroscopic methods for analysis of organic compounds.

3 .

Student will be able to derive the structure of the organic compound based on different spectroscopy data.

Course Outcome

1 .

CO1: Understanding the fundamental principles, instrumentation, and theoretical aspects of spectroscopic techniques (UV-Vis, IR, NMR, and Mass Spectrometry) used in the analysis of organic compounds.
CO2: Interpretation and analysis of spectroscopic data to determine molecular structures using various spectroscopic methods.
CO3: Application of spectroscopic techniques in routine and advanced analysis, including industrial and research laboratory applications.
CO4: Problem-solving in structure elucidation using a single spectroscopic technique such as NMR.
CO5: Problem-solving in structure elucidation through an integrated approach using multiple spectroscopic techniques.

Essential Reading

1 .

D. C. Pavia, G. M. Lampman, G. S. Kriz, Introduction to Spectroscopy, THOMSON , 3 rd edition 2007

2 .

J. Mohan, Organic Spectroscopy, Narosa Publishing House , 2004

Supplementary Reading

1 .

. B. H. Williams, I. Flemming,, Spectroscopy Methods in Organic Chemistry, ., McGraw Hill, , 2005

2 .

Bessler and Silverstein, Spectroscopy of Organic Compounds, JOHN WILEY , 2001