National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

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Syllabus

Course Details

Subject {L-T-P / C} : BM6544 : Advanced Biochemical Engineering { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Krishna Pramanik

Syllabus

Module 1 :

Module I
Introduction. Review on biological Processes.
Module II
Enzyme kinetics: First and order second order reactions Enzyme inhibition multi-substrate enzyme kinetics Multisite allosteric enzyme kinetics
Module III
Enzyme immobilization Heterogeneous biochemical reaction systems, Reaction rates for immobilised enzymes,
Module IV
Heterogeneous system kinetic models for cell growth and product formation: unstructured, chemically structured and metabolic models.
Module V
Transport phenomena in bioprocess. Bioreactor design and analyses

Course Objective

1 .

To analyze reaction kinetics and reactor systems involved in complex enzyme kinetics

2 .

reaction kinetics and reactor systems involved in complex enzyme kinetics

3 .

To analyze the reaction kinetics and various fermenter systems involving multicomponent, multiphase microbial cell kinetics

4 .

To analyze transport phenomena involved in bioprocess. Bioreactor design & analysis, and scale up

Course Outcome

1 .

The students will be able..
1. To learn and analyse the reaction kinetics and reactor systems involved in complex enzyme kinetics
2. To analyze reaction kinetics and reactor systems involved in complex enzyme kinetics
3. To calculate the complex microbial growth kinetics and evaluate the performance of different bioreactor/fermenter systems.
4. To design and analyze bioreactor, and to scale up the bioreactor systems.

Essential Reading

1 .

J. E. Bailey and D. F. Ollis, Biochemical Engineering Fundamentals, McGraw-Hill Publishing Co. New York

2 .

Irwin H Segel, Biochemical Calculations, Wiley and sons

Supplementary Reading

1 .

P. M. Doran, Bioprocess Engineering principles, Academic Press,

2 .

M. L. Shuler and F. Kargi, Bioprocess Engineering- Basic concepts, Prentice Hall,