National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

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Syllabus

Course Details

Subject {L-T-P / C} : BM6537 : Advanced Instrumentation in Bioengineering { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Sivaraman J.

Syllabus

Module 1 :

Module 1: Fundamentals of Advanced Instrumentation (Hours 7)
Overview of advanced instrumentation systems in bioengineering, Signal conditioning and data acquisition: Concepts, design, and applications, Principles of bio-electronic interfacing and microcontroller-based systems Real-time data monitoring and processing for biomedical applications.

Module 2: Sensors and Actuators in Bioengineering (Hours 7)
Advanced biosensors: Electrochemical, optical, piezoelectric, and nanobiosensors, Smart sensors for physiological monitoring and wearable devices, Actuator technologies: Piezoelectric, pneumatic, and shape-memory alloy-based systems, Microfluidic and nanofluidic devices in biomedical diagnostics and therapeutics, Integration of sensors and actuators in biomedical devices

Module 3: Advanced Imaging and Diagnostic Instrumentation (Hours 8)
Principles of emerging imaging modalities: Optical coherence tomography (OCT), hyperspectral imaging, and elastography, AI-powered diagnostic tools and handheld imaging devices, Image-guided interventions: Technologies, applications, and innovations, Safety standards, calibration, and regulatory considerations in diagnostic instrumentation

Module 4: Therapeutic Instrumentation and Devices (Hours 7)
Laser-based therapeutic technologies: Photodynamic therapy, laser ablation, and low-level laser therapy, Surgical robotics: Principles, instrumentation, and clinical applications, Bioprinting systems: Instrumentation, techniques, and bio-inks, Advanced instrumentation for targeted drug delivery systems

Module 5: Emerging Trends and Challenges in Bioengineering Instrumentation (Hours 7)
Integration of artificial intelligence (AI) and the Internet of Things (IoT) in biomedical devices, Implantable and portable bio-instrumentation technologies, Miniaturization and nanotechnology in instrumentation Ethical, legal, and regulatory aspects of advanced biomedical devices

Course Objective

1 .

To provide in-depth knowledge of advanced instrumentation technologies used in bioengineering.

2 .

To equip students with skills for designing and applying sensors and actuators in biomedical systems.

3 .

To introduce emerging imaging and therapeutic tools for healthcare applications.

4 .

To explore the challenges and opportunities in modern bioengineering instrumentation.

Course Outcome

1 .

By the end of the course, students will:
1. Understand the principles and applications of advanced instrumentation in bioengineering.
2. Develop and analyze instrumentation systems for biomedical research and healthcare solutions.
3. Address challenges related to miniaturization, safety, and regulation in biomedical devices.
4. Innovate and contribute to the development of next-generation bioengineering instruments and systems
5. Understand the principles and applications of therapeutic tools for healthcare applications.

Essential Reading

1 .

Manz, N. Pamme and D. Iossifidis, Bioanalytical Chemistry, World Scientific Publishing Company

2 .

R. S. Khandour, Handbook of Analytical Instruments, McGraw Hill

Supplementary Reading

1 .

John Enderle, Susan Blanchard, Joseph Bronzino, Introduction to Biomedical Engineering, Academic Press

2 .

H. H. Willard, Instrumental Methods of Analysis, CBS Publishers