Syllabus

Module 1 (Advanced bioreactor technologies) (10 hours)
Introduction to bioreactor design
Design aspects and process calculations for membrane bioreactors, airlift and hybrid bioreactors, Perfusion and continuous cultures, solid state fermentation systems, bioreactors for multiphase systems, scale up and scale down studies, Industrial case studies
Module 2 (Bioreactor process control) (6 hours)
Sensors and instrumentation in advanced bioreactors
Real time process monitoring and control
Bioreactor diagnostics
Module 3 (Transport phenomenon in bioreactors) (10 hours)
Mass transfer in bioreactors
Heat transfer in bioreactors
Application of CFD in designing bioreactors
Module 4 (Future trends and emerging bioreactors) (10 hours)
Bioreactor engineering for recombinant proteins
Microfluidic reactors and Lab on a Chip bioreactors
Bioreactors for carbon capture

To learn design aspects of advanced bioreactors

To aware students about process control in advanced bioreactors

To learn the intricacies of transport phenomenon in advanced bioreactors

To study design aspects of emerging bioreactors

1. Students will be able to design advanced bioreactors for production of microbial products
2. Students will be able to design reactors for animal cell and plant cell cultivation and their products
3. Students will be able to design process control of advanced bioreactors
4. Students will be able to apply CFD for designing transport phenomenon in bioreactors
5. Students will be able to design emerging bioreactors

Hai, F.I., Yamamoto, K., Lee, C., Membrane Biological Reactors: Theory, Modeling, Design, Management and Applications to Wastewater Reuse., IWA publishing

Bao, J., Ye, Q. and Zhong, J.J., Bioreactor Engineering Research and Industrial Applications II, Springer

J E Bailey and D F Ollis, Biochemical Engineering Fundamentals, Mc Graw& Hills

M. L. Shuler and F. Kargi, Bioprocess Engineering: Basic Concepts, Prentice Hall of India

Mandenius, C.F., 2018. Conceptual design of micro-bioreactors and organ-on-chips for studies of cell cultures. Bioengineering, 5(3), p.56.