National Institute of Technology Rourkela

राष्ट्रीय प्रौद्योगिकी संस्थान राउरकेला

ଜାତୀୟ ପ୍ରଯୁକ୍ତି ପ୍ରତିଷ୍ଠାନ ରାଉରକେଲା

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Syllabus

Course Details

Subject {L-T-P / C} : BM6439 : Essential Concepts of Cell and Molecular Biology for Bioengineers { 3-0-0 / 3}

Subject Nature : Theory

Coordinator : Kasturi Dutta

Syllabus

Module 1 :

Biomolecules: structure and function, Introduction to unicellular and multicellular systems. From cells to tissue: different forces playing across the length scale. Allometric relationships, Understanding biology in terms of number, Brief outline of important cellular processes, Central dogma of molecular biology, Brief overview of transcription and translation, Cell-cell and cell-material interaction, Cell adhesion, migration, proliferation, differentiation and cell death, Endocytosis, Mechano-transduction, Electrophysiology of cells, action potential, bio-impedance, pathogenesis, Stem cell, Cell culture and characterization of cells, Concepts of Immuno-compatibility, Interface of cell biology with pharmaceutical technology, nanotechnology, biomedical engineering, tissue engineering and regenerative medicine. Cells as therapeutics, bioreactor, biosensor, biobattery and bioengineering building block. Ethical aspects of applied cell biology

Course Objective

1 .

To provide overview of different aspects of living system.

2 .

To establish co-relation among physical processes and biological systems in terms of engineering principles.

3 .

To highlight the prospective application of basic concept of biology in other fields and vice versa.

Course Outcome

1 .

after completion of this course students will be able to
decipher a complex biological process in terms of engineering principle wherever applicable,
analyze and appreciate a biological phenomenon both qualitatively and quantitatively,
able to apply the knowledge and concept of biology in translational research,

Essential Reading

1 .

B.Alberts, D.Bray, K. Hopkin, A.Jhonson, Essential of cell biology, Garland Science,2013 , ISBN-13: 978-0815344544

2 .

R. Milo, R. Phillips, Cell Biology by the Numbers, Garland Science,2015 , ISBN-13: 978-0815345374

Supplementary Reading

1 .

R.I Freshney, Culture of Animal cell: A manual of basic techniques and specialized application, Wiley-Blackwell ,2016 , ISBN-13: 978-1118873656

2 .

A.T. Jhonson, Biology for Engineers, CRC Press 2010 , ISBN-10: 9781420077636