Syllabus

Introduction, architecture and mechanics of biological cells, mechanical analysis of cytoskeletal filaments, membranes, and adhesions and the unique instrumentation tools used for in vitro characterization of cells, various models used to describe cell mechanics.
Mechanotransduction, review of basic cell biology, role of Mechanotransduction in human physiology which converts mechanical force into a biochemical response in a cell, theoretical and experimental advancements in the field of cell mechanics, cells behaviour as a biomechanical material at the nano and microscale.

To study the importance of mechanobiology for organ and tissue development, growth, adaptation, regeneneration and disease

At the end of the course, the student will be able to:
1.To explain the use and importance of constitutive models for the quantification of mechanical signals
2. To situate the importance of mechanobiology in the context of biomedical engineering.

Jacobs, Huang, & Kwon, Introduction to Cell Mechanics and Mechanobiology, Garland Science, ISBN: 0815344252

Mofrad & Kamm,, Cytoskeletal Mechanics – Models and Measurements, Cambridge University Press, ISBN: 0521846374

Boal, Mechanics of the Cell, Cambridge University Press, ISBN: 0521796814

Bray, Cell Movements, Garland Press, ISBN: 0815332823.